The malaria parasite may be gaining resistance against artemisinin, the drug most often used to try and save children with mosquito-borne malaria.

As resistance grows, treating severe malaria in African children becomes more challenging. Hence, new guidelines and treatment strategies are needed to combat this devastating mosquito-borne disease. Artemisinin Partial Resistance in Ugandan Children With Complicated Malaria - (https://jamanetwork.com/journals/jama/fullarticle/2826317)

Scientists have detected resistance to artemisinin, a key malaria drug, for the first time among children in Africa with severe disease. The continent accounts for 95% of all deaths from malaria globally, and children are the most badly affected.

The 10.3% of participants that experienced recrudescence -- recurrent malaria caused by the same strain of P. falciparum as the initial infection after treatment with artesunate followed by artemether-lumefantrine combination therapy -- was also notable John told MedPage Today.

Discover new findings on partial artemisinin resistance in Ugandan children with severe malaria. Study reveals a potential need for revised malaria treatment protocols in Africa.