Self26d
Meet The New Drugs That Can Slow Down Early Alzheimer’s
But in just the past year and a half, two anti-amyloid drugs—lecanemab (Leqembi) and donanemab (Kisunla)—that can slow the progression of early Alzheimer’s disease have been approved in the US.
Medical Xpress25d
An electrochemical field is key to how dementia precursors 'break bad,' says new research
One such assembly, amyloid beta peptide, is synonymous with dementia, but researchers were not certain how these peptide assemblies "break bad" and what really causes them to assemble. Now ...
Nature3mon
Amyloid β interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease
Amyloid β protein (Aβ) deposition in the brain is a hallmark of Alzheimer's disease (AD). The fibrillar form of Aβ is neurotoxic, although the mechanism of its toxicity is unknown. We showed th ...
Nature4y
Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein
Amyloid precursor protein (APP) plays a central role in Alzheimer disease. A proteolytic-breakdown product of APP, called β-amyloid, is a major component of the diffuse and fibrillar deposits ...