Treatment modalities include liver transplantation for transthyretin-related (ATTR ... of amyloid. N-terminal probrain natriuretic peptide and troponin for assessing (severity of) cardiac involvement.

and cardiac hypertrophy 6. Neuropathy that begins at the toes and moves up is a common feature of hereditary ATTR amyloidosis. Rapid disease progression and lack of response to prior therapies for ...

These fibrils form the amyloid protein, which is associated with CV damage and premature mortality in patients with ATTR-CM. The approval is based on the results of the phase 3, double-blind ...

AI tools that analyze echocardiograms and electrocardiograms can identify those at higher risk of heart disease-related death, a study at the ACC meeting showed.

“In our study, in 97 patients, we were able to show high levels of sensitivity and specificity for detection of cardiac amyloid in ATTR, AL, and other rare types of systemic amyloidosis ...

Vutrisiran improved mortality and recurrent CV risks independent of disease severity and improved several other endpoints for ...

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, today announced moderated poster presentations of new data from the landmark ...

124 I-evuzamitide PET/MRI demonstrated uptake in multiple organs with amyloid deposition ... with ~95% of ATTR and 75% of AL patients having cardiac involvement. Other rare types of systemic ...

PET/CT, the first pan-amyloid diagnostic imaging agent, demonstrated 100% sensitivity and specificity for the diagnosis ...