has been considered to be the central regulator of autophagy, because TOR inhibition with rapamycin (Rap) induces autophagy. However, it is now clear that there are also TOR-independent types of ...
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Light-activated compound offers hope for overcoming drug resistance in cancer treatmentMore information: Mingyu Park et al, Rational Design of Biocompatible Ir(III) Photosensitizer to Overcome Drug‐Resistant Cancer via Oxidative Autophagy Inhibition, Advanced Science (2024).
Conversely, inhibition of spermidine synthesis, using appropriate inhibitors, counteracts the benefits of autophagy on lifespan through intermittent fasting. The results of the research highlight ...
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