After all, autophagy is a degradative mechanism that is part of the lysosomal system, and it was de Duve who carried out the pioneering biochemical work that helped lead to the discovery of the ...

Autophagy, derived from a Greek word, the "self-eating" nature refers to an interesting cellular process as part of the body's own recycling mechanism for cellular damage or components that have ...

How is it controlled by the cell? Today, research on autophagy is a growing field with increasing prominence because understanding the basic mechanisms of autophagy is key to understanding how ...

At its core, autophagy is a survival mechanism that allows cells to adapt to changing conditions and stress. When activated, the process identifies damaged proteins, dysfunctional mitochondria ...

The study is published in Developmental Cell. "The mechanism we discovered enables autophagy to devour as much damaged ...

Scientists have discovered how cells initiate waste recycling and form ‘garbage bags,’ a crucial process for health. This ...

The study, published in EMBO Molecular Medicine, shows that a process called chaperone-mediated autophagy (CMA) may function as a natural defense mechanism against metastases. Cancer remains one ...

A study published this month (August 14) in Neuron finds a link between autism and defects in synaptic pruning in humans, and also demonstrates that repairing broken pruning and autophagy mechanisms ...

Professor Noboru Mizushima's research project is focusing on autophagy, and is trying to clarify various questions related to intracellular degradation. A common mechanism of eukaryotes, from yeast to ...

Ubiquitin-specific proteases play a critical role in regulating cell death pathways in breast cancer, affecting tumor ...