Kaley Cuoco played Penny on "The Big Bang Theory," the pretty girl who befriends (and marries one of) the nerds who make up the show's cast. She was one of the hit sitcom's biggest breakout stars.

From the mean streets of Los Angeles to the desolate desert of New Mexico, Cruz must contend with a brutal Russian boxer, three brash LAPD detectives, an aged billionaire looking for the Big Bang ...

With his crippling shyness, selective mutism around women, and hilarious over-reliance ... As a core member of the original ...

While the show includes multiple main cast ... Big Bang Theory, Mrs Wolowitz initially had mixed feelings about Howard's relationship with Bernadette. Being an overprotective mother, she was skeptical ...