Under normal conditions, bilirubin formed from the catabolism of heme is taken up and conjugated by the liver, secreted into the bile and then transported through the bile ducts to the duodenum.

Future research will likely explore how gut microbial bilirubin metabolism influences our health, from neonatal jaundice and IBD to its relationship with obesity, insulin resistance, and ...

Conjugation of bilirubin and delivery to the intestine doesn't necessarily lead to excretion of the substance. Neonatal intestines contain beta-glucuronidase, an enzyme capable of reducing ...