Over the last 20 years, researchers in biology and medicine have created Boolean network models to simulate complex systems and find solutions, including new treatments for colorectal cancer.

But gene regulatory networks can be large and complex. One of the Boolean models in the researchers’ dataset involves more than 300 genes. And along with negative feedback loops, gene regulatory ...

A meta-analysis of Boolean network models reveals design principles of gene regulatory networks. Science Advances , 2024; 10 (2) DOI: 10.1126/sciadv.adj0822 Cite This Page : ...