Lewis, J. (2009) Exploring the accuracy and practicality of a new two-step algorithm for C. difficile testing. Nursing Times; 105: 16, early online publication. C. difficile infection is a major cause ...

testing is highly sensitive for C difficile detection. Additionally, some clinical laboratories have implemented a 2-step testing algorithm, consisting of a PCR test and toxin enzyme immunoassay ...

Clostridium difficile infection ... is the Simplexa C. diffcile Direct Assay, An evaluation of this technology was conducted for the purpose of determining its overall performance and potential ...

In a longitudinal cohort study, 2-step testing was associated with a reduction in the incidence of hospital-onset C difficile infection and decreases in antibiotic use over time. Use of 2-step ...

Two-step testing was associated with a decrease in hospital-onset C. difficile infection. Similar decreases were observed in utilization rates for oral vancomycin and fidaxomicin. “While there ...

A major challenge in C. difficile testing is that no single test ... diff toxins A/B assay outperformed PCR, EIA, and two multistep algorithms. CDI presents challenges to hospital infectious ...

WASHINGTON, D.C. — A single-step nucleic acid amplification test in combination with a strict stool rejection policy detected more cases of Clostridium difficile compared with a combination of ...

Simply adding an admission screening question and a 2-step testing algorithm sharply decreased the number of Clostridioides difficile infections (CDI) in the year after implementing the interventions.

Director of Microbiology and Infectious Diseases Molecular Diagnostics at University of Louisville Hospital ...