A patient in Louisiana became severely ill after contracting Highly Pathogenic Avian Influenza (HPAI), the US Centers for Disease Control and Prevention (CDC) announced in a statement on Thursday. This is the first serious case of bird flu affecting a human reported in the US since the outbreak began.

The Centers for Disease Control and Prevention (CDC) has confirmed the first severe case of bird flu in the United States, noting it has shown a “concerning” mutation, leaving health experts to warn about the risk of another pandemic.

Growing concerns surrounding the transmission of H5N1 bird flu. The CDC reports that samples collected from a severely ill patient in Louisiana showed signs of mutation, as they differ from the samples collected from sick and dead birds believed to have infected the man in the first place.