Feb. 13, 2025 — A new study unravels the relationship between mitofusins (mitochondrial proteins) and autophagy. Using gene editing with CRISPR-Cas9, the team has been able to study these ...

When the CRISPR Cas9 protein is added to a cell along with a piece of guide RNA, the Cas9 protein hooks up with the guide RNA and then moves along the strands of DNA until it finds and binds to a ...

A new study in mice documents frequent undesirable repeats of DNA ... In less than a decade since its adaptation to a genome-editing technique, CRISPR-Cas9 has been used on lab animals and cells ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have ... mouse lines that will allow researchers to study complex genetic interactions and their effects ...

CRISPR-Cas9 burst onto the broader scientific scene in 2012 when a team led by Jennifer Doudna showed that it could be modified to target and cut specific segments of DNA. The CRISPR half of the ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have ... mouse lines that will allow researchers to study complex genetic interactions and their effects ...