With a few exceptions, eukaryotic chromosomes have a single centromere that ensures their accurate segregation during mitosis. Chromosomes that lack centromeres segregate randomly during mitosis ...

The improper segregation of chromosomes during cell division leads to abnormalities that disrupt the proper functioning of the cell. Cells with an abnormal number of chromosomes consequently ...

Scientists at EMBL have captured how human chromosomes fold into their signature rod shape during cell division, using a ...

In eukaryotes, segregation of duplicated chromosomes is performed by the mitotic spindle, a cellular machine composed of microtubules and their associated proteins. Spindles are built from ...

Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For ...

One of the most powerful weapons that cancer cells have at their disposal is CIN, which involves randomly shuffling their chromosomes each time they divide. (See illustration on opposite page.) Errors ...

Chromosomes contains all genome information. During mitosis spindles attach a special structure of chromosome, which is called "centromere." In this study, we clarified how centromeres are formed ...

Scientists have known for decades, however, that selfish genes can subvert Mendelian segregation to increase their frequency in the next generation, a phenomenon known as meiotic drive. The Madeira ...

Chromo is one of the healthy calves born during assisted reproductive technology research that looked at the relationship between chromosomal segregation errors and embryonic loss in cattle.

though it was different in its segregation into sperm cells, the accessory chromosome was indeed a true chromosome (Sutton, 1902). The notion that sex could be determined by chromosomes was a new ...

Numerical chromosomal abnormalities (aneuploidies) -- the presence of an extra chromosome (trisomy) or a missing chromosome (monosomy) -- result from segregation errors during cell division ...