"HMGA1 functions like a molecular 'key' that 'opens' regions of the genome to activate stem cell genes in mutant colon cells, which in turn drives tumor development and progression," Resar explains.

March is Colon Cancer Awareness Month. It’s a reminder about how important it is to get checked for what’s now the ...

Colon cancer has been on the rise in Americans under 50 for the last three decades, but it’s not exactly clear why. Researchers suspect poor diet, obesity, sedentary lifestyles, environmental ...

Colon cancer is one of the most common cancers in the U.S. for both men and women. However, early screening can help catch ...

Scientists at Northwestern Medicine have discovered that blocking a protein called GATA6 in mice with colon cancer slowed ...

"This is the first time we show that GATA6 is a global regulator and controls many key oncogenes in colon cancer," said Feng Yue, Ph.D., the Duane and Susan Burnham Professor of Molecular Medicine ...