Drug substance purification by crystallization is a key interface in going from drug substance synthesis to final formulation and can often be a bottleneck in process efficiency. There has been ...

Crystallization is a major separation process in the pharmaceutical industry. Most crystallizations are performed batchwise, but there is great incentive for switching to continuous operation. We have ...

An oscillatory flow baffled crystallizer (OFBC) is utilized as a continuous spherical crystallization unit. Spatially distributed solvent addition along the length of the OFBC divides the system into ...

Crystallization is a major separation process in the pharmaceutical industry. Most crystallizations are performed batchwise, but there is great incentive for switching to continuous operation. We have ...