AI tools help uncover enzyme mechanisms for lasso peptides
Two enzymes, a peptidase and a cyclase, then collaborate to convert a linear precursor peptide into the distinctive knotted ...
Risk gene for bipolar disorder decoded
More information: Paromita Sen et al, A bipolar disorder-associated missense variant alters adenylyl cyclase 2 activity and ...
Nature6y
An example of signal transduction cascade involving cyclic AMP
The signal transduction cascade begins when adenylyl cyclase, a membrane- bound enzyme, becomes activated by G-protein molecules associated with the adrenergic receptor. Adenylyl cyclase creates ...