a computational tool that helps match tumors and cell lines based on gene expression profiling data. Because cell lines are grown in labs, often for decades, they do not completely reflect the ...

We propose a Bayesian statistical framework for gene ... data. The model dynamically selects a background data set on the basis of similarity to the individual sample, which is then used to identify ...

Complex traits are influenced by genes and the environment, but especially the latter is difficult to pin down. This important study uses C. elegans to demonstrate that non-genetic differences in gene ...

The cancer phenotype, however, likely reflects the changes in the expression patterns of hundreds or even thousands of genes that occur as a consequence of the primary mutation of an oncogene or a ...