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HIV in cell culture can be completely eliminated using CRISPR-Cas gene editing technology, increasing hopes of cure
Functioning like molecular scissors with the guidance of guide RNA (gRNA), CRISPR-Cas can cut the DNA at designated spots. This action facilitates either the deletion of unwanted genes or the ...
BioTechniques1y
Reining in CRISPR-Cas9 with [C]gRNA
In the CRISPR-Cas9 gene editing system, the Cas9 nuclease is introduced into cells and directed to the location of interest with synthetic guide RNA (gRNA), where Cas9 cleaves the two DNA strands. Off ...
Nature3y
Groundbreaking first nano molecular drill crosses cell membranes to safely deliver small molecules, biological therapeutics and nucleotide-based drugs
It can deliver its payloads, including genome editing compounds such as CRISPR-Cas9, gRNA and DNA, directly to the targeted nucleus without harming the cell. It can be programmed to recognize cell ...