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Review highlights the interplay of TGF-β and HIPPO pathways in liver regeneration and disease
Disruptions in the regulation of TGF-β and HIPPO pathways contribute to liver diseases. In fibrosis, the TGF-β pathway promotes the activation of hepatic stellate cells, leading to extracellular ...
BioWorld11d
Study finds Hippo pathway aberrantly activated in NPH1 models, unveiling Kibra as a potential target
Nephronophthisis (NPH) is a recessive cystic kidney disease responsible for 10% to 20% of pediatric end-stage renal disease cases. NPHP1 (nephrocystin 1) is the most frequently implicated among over ...