A native function for RAN translation and CGG repeats in regulating fragile X protein synthesis. Nature Neuroscience , 2020; DOI: 10.1038/s41593-020-0590-1 Cite This Page : ...

"The repeats function like a switch, slowing down protein production and then quickly turning things back on," explains principal investigator Peter Todd, M.D., Ph.D., ...

The inactivation of BRCA2, a suppressor of breast, ovarian and other epithelial cancers, triggers instability in chromosome structure and number, which are thought to arise from defects in DNA ...

GATA simple sequence repeats (SSRs) are located throughout vertebrate genomes in a non-random fashion. The authors show that these act as enhancer blocker elements in both human cells and ...

The repeats function like a switch, slowing down protein production and then quickly turning things back on." Peter Todd, M.D., Ph.D., principal investigator, associate professor of neurology at ...

Over half of our genomes are made of repeating elements within DNA. Research to date has focused on how these expanded repeats can cause disease, but little attention has been given to their normal ...