Three biochemical pathways activate the complement system: the classical complement pathway, the alternative complement pathway, and the lectin pathway. Most of the proteins and glycoproteins that ...

IgA vasculitis can present as a glomerulonephritis histologically indistinguishable from IgA nephropathy (IgAN). In IgAN, the alternative and lectin pathways mediate glomerular injury and contribute ...

The lectin pathway is one of three pathways by which the complement system can be activated. This pathway is initiated by the binding of mannose-binding lectin (MBL), collectin 11 (CL-K1), and ...

The ascidian complement system — which consists of MBL-like lectin, ficolins, two MASPs, C3 and C3 receptor — functions in an opsonic manner, and it constitutes a primordial complement system ...

Figure 1 A schematic diagram showing the three complement activation pathways converging at a common terminal route of forming the membrane attack complex (MAC). The labels of the components of the ...

The complement system is composed of three pathways: the classical pathway, the alternative pathway, and the lectin pathway (Figure 1). The classical pathway is typically activated by antibody.

MASP-1 and the lectin pathway Behind the discovery of the central role of MASP-1 in the complement system is, apart from Soeren Egedal Degn, also the Aarhus professors Jens Chr. Jensenius and ...

The lectin pathway of the complement system — a system that enhances the body’s ability to clear invaders — may underlie the clinical manifestation of systemic lupus erythematosus (SLE), new research ...

The complement system is a part of the immune system that enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, ... Complement ...