Going from gene sequence to protein function presents a great challenge to genome biology. In the September 15 EMBO Reports, Simpson et al. suggest that the systematic identification of subcellular ...

Localization of function in the brain has been a topic in experimental brain sciences since the classical electrical stimulation studies on the dog cortex that were published in 1870 by Fritsch ...

The human brain is a fascinatingly complex organ with specialized structures associated with distinct functions. Classical and recent studies on brain localization propose that Broca’s area underpin ...

For example, identify the cellular compartment in which ILK becomes phosphorylated by PAK1. Considering that PAK1 localizes in the nucleus upon EGF treatment ... Phosphorylation-dependent regulation ...