Profluent’s latest protein language model incorporates structural and functional context to decode the language of biology for fine-tuned protein design By Fay Lin, PhD August 5, 2024 ...

Existing models allow us to decode the structures of molecules, but to make new medicines we need to be able to design them. Neo-1, for the first time, allows for this in a single unified model.” ...

image: (a) Protein sequence-structure co-design with PocketGen; (b) Dual-layer graph Transformer encoder; (c) Pre-trained protein language model for sequence prediction and efficient fine-tuning.

Germany, have developed a new method that makes it possible for the first time to image the three-dimensional shape of ...

A small molecule binds to an OX2 protein. The new foundation model Boltz-2, developed by researchers at MIT and Recursion, achieves state-of-the-art performance in protein binding affinity prediction.