What can we use iPS cells for? ES cells were originally derived from the inner cell mass (ICM) or epiblast of mouse embryos. These cells exhibit an almost unlimited proliferative capacity in ...

After the targeting vector is made, it is used to knock out one copy of the target gene in mouse embryonic stem (ES) cells (Figure 2). But why must mouse ES cells be used? Why can't the targeting ...

Bush's decision in August 2001 to permit federal financing for research on human embryonic stem (ES ... early precursor cells and spread them out on a feeder layer of mouse cells to produce ...

Using CRISPR-based engineering methods to prompt stem cells to organize into embryo-like structures, scientists were able to create 'programmable' cellular models of embryos without ever experimenting ...

UCSC scientists have used CRISPR to develop programmable embryoids that can be used to study early embryo development and ...

In the new study, mice were created through genetic editing of mouse embryonic stem cells targeting a class of mammal-specific genes known as imprinted genes, of which there are about 200 ...

Mammary organoids derived from mouse embryonic stem cells could offer clues into mammary gland developmental origins and help researchers study breast cancer. “When we use embryonic stem cells, they ...

Converting one type of cell to another—for example, a skin cell to a neuron—can be done through a process that requires the ...