CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

Could advances in CRISPR technology be the solution? In the last decade, a new immunotherapy tool has entered the clinic. T cells engineered to express chimeric antigen receptors, known as CAR T ...

The newly discovered gene that sets us apart from Neanderthals - This unique adaptation gave Homo sapiens an evolutionary ...

A specific gene variant seen in people is likely one of many that contributed to the development of language in modern humans ...

Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, ...

I will discuss how bacterial CRISPR adaptive immune systems inspire creation of powerful genome engineering tools, enabling advances in both fundamental biology and applications in medicine and ...

But as it turns out, CRISPR/Cas9 gene editing is a completely natural function in which bacteria catalogs its interactions with viruses by taking a snippet of the virus’ genetic material and ...

In the world of biopharmaceutical innovation, 2024 will be remembered as CRISPR’s breakout year. In the spring, five patients with sickle cell disease began treatment with Casgevy, the first FDA ...

CRISPR gene editing takes advantage of a system already found in nature. CRISPR's "genetic scissors" evolved in bacteria and other microbes to help them fend off viruses. Their cellular machinery ...

A new study links a particular gene to the origins of spoken language, proposing that a protein variant found only in humans may have helped us develop speech.

A CRISPR-based system that erases itself from fly populations may offer a safer approach to tackling insecticide resistance ...