CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

Gene-edited crops may help adaptation to climate change The centre, funded primarily by the British government, operates on ...

■ ...

A specific gene variant seen in people is likely one of many that contributed to the development of language in modern humans ...

Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, ...

This study presents an optimized CRISPR-Cas12a system for large-scale genetic screening, revealing critical genes involved in ...

In the world of biopharmaceutical innovation, 2024 will be remembered as CRISPR’s breakout year. In the spring, five patients with sickle cell disease began treatment with Casgevy, the first FDA ...

A new study links a particular gene to the ancient origins of spoken language in humans. When put in mice, it changed the way ...

CRISPR gene editing takes advantage of a system already found in nature. CRISPR's "genetic scissors" evolved in bacteria and other microbes to help them fend off viruses. Their cellular machinery ...

Traditional diagnostic methods, such as bacterial culture and PCR-based testing, can take 24–72 hours, delaying critical treatment decisions. In contrast, PathCrisp enables direct detection from ...