While genetically manipulating mice to produce neprilysin is useful experimentally, to treat people with the disease, we need a way to do it using medication. Neprilysin pills or an injection are ...

The dual-action agent LCZ696 blocks the angiotensin II receptor (via a valsartan moiety) and inhibits neprilysin (via an AHU377 moiety). In a phase II trial, this drug “demonstrated superior ...

Published in the scientific journal Science Signaling on August 6, the study examines dopamine's role in promoting the production of neprilysin, an enzyme that can break down the harmful plaques ...