Progressive supranuclear palsy (PSP ... The most specific diagnostic feature is the supranuclear vertical gaze palsy (inability to look up and down). Difficulty moving one's eyes in the downward ...

Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are sporadic four-repeat tauopathies that have characteristic clinical and neuropathologic profiles, but also share ...

Inflammatory Trigger a New Clue in Alzheimer's Jan. 6, 2023 — Researchers have identified a new trigger of brain inflammation in Alzheimer's disease and progressive supranuclear palsy ...

Historically, frontotemporal lobar degeneration (FTLD), corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP) were classified on the basis of distinct clinical and pathological ...

More information: Miriam Scarpa et al, Post mortem validation and mechanistic study of UCB‐J in progressive supranuclear palsy patients' brains, Alzheimer's & Dementia (2024). DOI: 10.1002/alz.14409 ...

The levels of neurofilament light chain in the cerebrospinal fluid of people with progressive supranuclear palsy were found to be higher than those of people with Alzheimer's disease (effect size = ...

and cerebral cortex of patients with progressive supranuclear palsy (PSP). This group has now shown that a low ratio of these tau forms reliably differentiates patients with PSP from controls and ...