While the San Francisco 49ers season has been a disaster, two bright spots have been All-Pro tight end George Kittle and his ...

The Detroit Lions finally got revenge on the San Francisco 49ers on a day that Dan Campbell decided to play his starters to ...

The San Francisco 49ers injury-plagued season continued on Monday night in a 40-34 loss to the Detroit Lions. Star ...

Well, it wasn’t as ugly as it could’ve been. The San Francisco 49ers fell to the Detroit Lions in an NFC championship game ...

On Monday, Reader will take the field with the Lions as they venture back to the site where they suffered a similar feeling ...

The San Francisco 49ers fell to 6-10 on the year with a "Monday Night Football" loss in Santa Clara against the Detroit Lions ...

San Francisco 49ers quarterback Brock Purdy reportedly suffered a nerve issue in his right elbow late in Monday's 40-34 loss against the Detroit Lions ...

The 49ers (6-9) were officially eliminated from playoff contention Sunday, even before kickoff of their 29-17 defeat to the ...

The defending NFC champion San Francisco 49ers were eliminated from the playoffs before their loss vs. Miami on Sunday ...

As of Dec. 22 the San Francisco 49ers' odds of winning the Super Bowl are listed at +100000. In their last game, the 49ers fell to the Los Angeles Rams 12-6. Brock Purdy had 142 yards on 14-of-31 ...

NFL Week 18 odds, picks, predictions, TV channel, streaming information for Sunday football game between San Francisco 49ers ...

If Brown can't suit up against the Lions, Talanoa Hufanga and Malik Mustapha would likely serve as San Francisco's ... he suffered during the 49ers' Super Bowl LVIII loss to the Chiefs in February.