The potential target, the FLT1 gene, contributes to the production of a protein, fetal hemoglobin, whose presence is already known to improve the lifespan of people with sickle cell disease.

Bluebird Bio and Xcellbio have entered into an agreement to support the commercialization of sickle cell gene therapy ...

Sebastien Beauzile became the first person in NY to be made symptom-free after undergoing a new type of gene therapy.

A marker linked to inflammation, C-reactive protein, may increase significantly during the follicular phase of the menstrual ...

A toolkit on hydroxyurea was designed to help parents of young children with sickle cell disease feel more confident about ...

“Now he’s producing normal adult hemoglobin in his parent cells ... s why he’s not having any symptoms related to his sickle cell disease.” For assurances, Beauzile had to stay in the ...

Anemia of chronic disease is caused by long ... abnormalities in red blood cells. Sickle cell anemia is an inherited hemolytic anemia with abnormal hemoglobin protein that causes red blood cells ...

Avianah Drakeford was born with sickle cell disease, a genetic disorder that negatively affects how blood moves around the ...

It's caused by a mutation of the hemoglobin gene ... those without sickle cell anemia live 20 years longer than those with the disease. Two new gene therapies hope to change that—and so far ...

"sickle cell disease (SCD) is a group of inherited blood disorders. Red blood cells contain hemoglobin, a protein that carries oxygen. Healthy red blood cells are round, and they move through ...

Collaborative research defines a novel approach to understanding how certain proteins called transcription factors determine which genetic programs will drive cell growth and maturation. The method, ...