When the mechanisms that replicate or repair mitochondrial DNA (mtDNA) fail, it can cause a wide range of syndromes for which ...

By combining the expansive REAL Space with the Recursion OS to predict small molecule compatibility with protein targets, the collaboration allows for the creation of smaller, highly focused libraries ...

The AI Small Molecule Drug Discovery Center will focus on three core areas: designing novel drug-like molecules using ...

Small molecules are low molecular weight molecules that include lipids, monosaccharides, second messengers, other natural products and metabolites, as well as drugs and other xenobiotics.

APRIL 8, 2020 — UTSA’s Doug Frantz, the Max and Minnie Tomerlin Voelcker Distinguished Professor in Chemistry and cofounder of the university’s Center for Innovative Drug Discovery, is screening small ...

A new company has entered the drug discovery space with what it calls a “chemistry-first” platform. Colorado-based Cime ...

Convelo’s approach is to target enzymes that are involved in remyelination that can be targeted with small-molecule compounds. The agreement with Sosei Heptares is more wide-ranging, with Roche ...

Pfizer (PFE) and Pioneering Medicines, Flagship Pioneering’s in-house drug discovery and development unit, announced an agreement to discover ...

AlphaFold 3, the improved version of the model used by Isomorphic Labs’ drug design engine, debuted last May. It can predict ...

These compounds are commonly found in medications ... This is crucial for making medicines, where even a small mistake in a molecule's structure can turn a helpful drug into something useless ...

Small-molecule inhibitors targeting viral proteins ... molecular docking analysis to screen a diverse library of natural compounds that could act against the spike proteins. By simulating ...

The Icahn School of Medicine at Mount Sinai has launched the AI Small Molecule Drug Discovery Center, a bold endeavor that harnesses artificial intelligence (AI) to revolutionize drug development.