Their findings, published in Nature Communications, offer new insights for dietary-based cancer treatments and highlight the critical role of the tryptophan metabolite indole 3-pyruvate (I3P ...

The research, published in the journal Nature Microbiology, reveals that when we eat a lot of dietary fiber, gut bacteria help turn tryptophan into healthy substances. But if we don't eat enough ...

Catabolism of the amino acid tryptophan by indoleamine 2,3-dioxygenase (IDO) produces immunosuppressive metabolites that can limit T-cell responses. Platten et al. tested the ability of several ...