Any obstacle or impediment to the smooth flow ... process can be pictured like a river. It's not unusual to hear people involved in production make frequent reference to "upstream" and "downstream ...

Single-use technologies are an increasingly popular choice for both upstream and downstream bioprocessing ... use technologies and represent “weak points” in the downstream process flow. Exacerbating ...

Downstream has always proved more problematical than upstream operations ... or integrated into one cohesive process flow for a fully continuous process. “The specific applications and approach ...

This process flow de-risks downstream from being the bottleneck for capacity to process the upstream material.” Ramos and her team used an integrated turn-key system developed by PAK ...