The major safety concerns in the top-down approach include TB, opportunistic infections, neutralizing antidrug antibody formation, autoimmunity, malignancy, lymphoma, cardiovascular or ...

At the World Congress of Gastroenterology in September, I had the opportunity to debate the benefits of a 'top-down' approach to the treatment of Crohn's disease, beginning with biologic (anti ...

The top-down approach relies heavily on photolithography, a process where light is used to transfer geometric patterns from a mask to a light-sensitive chemical photoresist on the substrate.

an emerging approach known as 'top-down' is beginning to make headlines, especially for the analysis of post-translational modifications (PTMs). PTMs often occur in different combinations on ...