The EMBO Journal2d
Rett syndrome: interferon-γ to the rescue?
In conclusion, this intriguing report builds on the work of many other groups by further unraveling MECP2 function in the ...
The EMBO Journal1d
Making contact away from home: a bacterial secreted effector mediates inter-organelle communication
Inter-organelle communication via the formation of membrane contact sites (MCS) is essential for cell homeostasis. Bacterial pathogens residing in membrane bound vacuoles have exploited this ...
The EMBO Journal7d
Reciprocal inhibition of NOTCH and SOX2 shapes tumor cell plasticity and therapeutic escape in triple-negative breast cancer
A NOTCH1-SOX2 negative feedback mechanism was linked with resistance to GSI. SOX2-induced inhibition of Notch signaling in ...
The EMBO Journal5d
TRPC5: a new entry to the chromaffin cell’s palette of ion channels that control adrenal response to hypoglycemia
Hypoglycemia is an extremely common side effect of insulin therapy experienced mainly by patients with type 1 diabetes ...
The EMBO Journal7d
Brain mitophagy in space and time
A new resource by Rappe et al (2024) now provides a spatiotemporal landscape of mitophagy changes during mouse brain aging at ...
The EMBO Journal12d
CMTM3 regulates neutrophil activation and aggravates sepsis through TLR4 signaling
Dysregulated neutrophil activation plays a significant role in sepsis. This study shows that the membrane protein CMTM3 is ...
The EMBO Journal8d
Liver DE(HP)toxification: luteolin as “phthalates-cleaner” to protect from environmental pollution
Environmental pollution is a major health problem that affects the health of individuals worldwide and is cumulative with ...
The EMBO Journal5d
Genetic linkage disequilibrium of deleterious mutations in threatened mammals
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The impact of negative selection against ...
The EMBO Journal6d
Leishmania protein KMP-11 modulates cholesterol transport and membrane fluidity to facilitate host cell invasion
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The first step of successful infection by any ...
The EMBO Journal9d
Sepsis-induced changes in pyruvate metabolism: insights and potential therapeutic approaches
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Sepsis is a heterogeneous syndrome resulting ...