To test the hypothesis that rapid and substantial bioavailability of the antidotes HI-6 oxime and dicobalt edetate can be achieved via the intraosseous (IO) route, plasma concentration-time profiles ...

Background: Current best practice for treating acute severe pain in children is to administer intravenous or intranasal opioid. Intranasal diamorphine offers less traumatic analgesia than the ...

Watanabe E, Nishikawa T, Ikawa K, Yamaguchi H, Abematsu T, Nakagawa S, et al. Trough level monitoring of intravenous busulfan to estimate the area under the plasma drug concentration-time curve in ...

Phase II Study of Area Under the Plasma-Concentration-Versus-Time Curve–Based Carboplatin Plus Standard-Dose Intravenous Etoposide in Elderly Patients With Small-Cell Lung Cancer .

Linear relationships between dose and the area-under-the-concentration-time curve to 3 hours (AUC 0-3) were found for both routes of administration.

The drug concentration-time profiles for nebulized fentanyl and IV fentanyl were shown to be similar when 100–300μg doses of fentanyl were administered to 15 healthy volunteers via inhalation ...

Plasma concentration-time curve for oxytetracycline (OTC) intravenous (IV), OTC long-acting (LA) intramuscular (IM), and OTC IM following administration of 20 mg/kg dose in Kilis Goat.

Phase II Study of Area Under the Plasma-Concentration-Versus-Time Curve–Based Carboplatin Plus Standard-Dose Intravenous Etoposide in Elderly Patients With Small-Cell Lung Cancer . If you have the ...