For the first time, he could see what a molecule of haemoglobin looked like in 3D. Using lectures and programmes from the BBC archive, Josephine McDermott tells the story of how his fellow ...

It has two primary functions: It transfers oxygen from your lungs to tissues ... 70% of the iron in your body and gives red blood cells their distinctive red color. Structure and Abnormalities There ...

Both oxygen and carbon dioxide are capable of combining with an iron-rich protein in the blood called haemoglobin. Haemoglobin carries oxygen to be exchanged at the working muscle and carbon ...

Figure 1: Crystal structure of porcine Hp–Hb. Electron micrographs showing Hp–Hb as a rigid structure 13 are supported by the presence of two nearly identical porcine Hp–Hb dimers in the ...

The intrinsic cytotoxicity of cell‐free haemoglobin (Hb) has hampered the development ... Here, we unraveled a rapid molecular reprogramming of the Hb structure‐function triggered by virulent ...

We hear about the moment Dr Max Perutz discovered the haemoglobin structure. Our expert is Professor Sir Alan Fersht, who is a chemist at the Medical Research Council Laboratory of Molecular ...

Figure 1: Structure of the oxidized αHb bound to AHSP. Although the αHb–AHSP interface resembles that of the α1–β1 complex between αHb and βHb (ref. 5) (both involving the hydrophobic ...

In other placental pathologies, including preeclampsia, extracellular free fetal haemoglobin (fHbF) is overproduced, where it inactivates the vasodilator nitric oxide (NO). We have previously shown ...

Both oxygen and carbon dioxide are capable of combining with an iron-rich protein in the blood called haemoglobin. Haemoglobin carries oxygen to be exchanged at the working muscle and carbon ...