Using genetically predicted metabolic reaction fluxes, the authors identify reactions that can amplify or buffer the effect ...

Aim: Drug–drug interactions (DDIs) are a widely recognized major cause of adverse drug reactions, but two other newly described important types of interactions also exist: drug–gene ...

The results, published in Cancer Discovery, prime the combination strategy for future clinical trials. Ben Stanger, MD, PhD, co-corresponding senior author, the Hanna Wise Professor in Cancer ...