C&EN19d
Chronic DSS-Induced Colitis Exacerbates Parkinson’s Disease Phenotype and Its Pathological Features Following Intragastric Rotenone Exposure
Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad 382355, Gujarat, India Department of Pharmacology and Toxicology, College of ...
Frontiers21d
Brain network and energy imbalance in Parkinson’s disease: linking ATP reduction and α-synuclein pathology
This ATP decline may result in α-synuclein accumulation, autophagy-lysosomal system impairment, neuronal network breakdown and accelerated neurodegeneration. We propose an “ATP Supply–Demand Mismatch ...
Frontiers23d
Recent advances in nanotechnology for Parkinson’s disease: diagnosis, treatment, and future perspectives
This review provides insights into the pathophysiology of Parkinson’s disease, highlighting the mechanisms of neurodegeneration, the role of alpha-synuclein, and the disruption of dopaminergic ...
ScienceAlert24d
Parkinson's Discovery Suggests We Could Already Have an FDA-Approved Treatment
In a paper published last year, an international team of scientists describes how the two proteins work together to help harmful alpha-synuclein protein clumps get into brain cells. "Now that we know ...