She was also areflexic. Electromyography confirmed severe sensorimotor peripheral neuropathy. Right sural nerve and rectal biopsies confirmed amyloidosis on Congo red staining. Laboratory studies ...

She has published extensively in peer-reviewed journals, and her research interests include myasthenia gravis, chronic inflammatory demyelinating polyneuropathy (CIDP), amyloid neuropathy ...

In these patients, hereditary ATTR amyloidosis usually presents as a peripheral sensory, motor and autonomic neuropathy starting in a person’s 20s or 30s. In the United States, the most common ...

leading to amyloid deposits in the heart, gastrointestinal tract, and peripheral nerves. Life expectancy is a median of 4.7 years after hATTR with neuropathy is diagnosed, less in hATTR patients ...

“Today’s approval of WAINZUA in Europe offers adults with hereditary transthyretin-mediated amyloidosis with polyneuropathy ... production and improves neuropathy impairment and quality ...

The drug has been approved to treat hereditary transthyretin-mediated amyloidosis in adult patients ... impairment – as determined by a neuropathy impairment score +7 (mNIS+7) – and serum ...