C&EN29d
Coupling Proximity Biotinylation with Genomic Targeting to Characterize Locus-Specific Changes in Chromatin Environments
Department of Molecular Medicine and Cancer Research Centre, Université Laval, Quebec, QC G1V 0A6, Canada CHU de Québec Research Centre, Quebec, QC G1V 4G2, Canada PROTEO-Quebec Network for Research ...
Frontiers4y
Nanoapproaches to Modifying Epigenetics of Epithelial Mesenchymal Transition for Treatment of Pulmonary Fibrosis
2015). In this review, we describe the mechanistic pathways how epithelial inflammation/injury promotes EMT and myofibroblast expansion and the evidence that BRD4 is an epigenetic regulator of EMT and ...
Frontiers4y
DNA Damage Induces Dynamic Associations of BRD4/P-TEFb With Chromatin and Modulates Gene Transcription in a BRD4-Dependent and -Independent Manner
The bromodomain-containing protein BRD4 has been thought to transmit epigenetic information across cell divisions by binding to both mitotic chromosomes and interphase chromatin. UV-released BRD4 ...