NAGA CITY —The Bicol police seized 52 grams of suspected shabu (crystal meth) worth more than P300,000 from a high-value individual during a buy-bust operation Wednesday in Labo town in ...

The first patient has been dosed in a phase 1b/2a trial (NCT06785636) of pocenbrodib, a CBP/p300 inhibitor, as a monotherapy and in combination with abiraterone acetate (Zytiga), olaparib (Lynparza), ...

GWM has introduced the P300 bakkie, which features a new powertrain and updates inside and out. Siya Mbaduli weighs in on the model with a few kilometres under his belt from the launch drive.

CLARK FREEPORT — The Tarlac City government did not receive P500,000 from a Chinese national who posted a photo of the donation online in 2022 and was recently suspected of being a spy.

This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...

Vertebrate embryos achieve developmental competency during zygotic genome activation (ZGA) by establishing chromatin states that silence yet poise developmental genes for subsequent lineage-specific ...

The ubiquitious HAT, P300, regulates hundreds of transcription factors such ... This mechanistic work has focused on the central role of BRD4 in mediating EMT and myofibroblast transition and initial ...

The bromodomain-containing protein BRD4 has been thought to transmit epigenetic information across cell divisions by binding to both mitotic chromosomes and interphase chromatin. UV-released BRD4 ...

On one hand, it interacts with many transcription activators such as members of the SWI/SNF complex and the acetylation reader BRD4, but on the other, high confidence interactions with known ...