Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Protein synthesis is an essential process, ...
Figure 7. NRL is associated with different types of R-loops. A) Metaplot of BRD4 (SRR4252658), CTCF (SRR4252685), NRL (Cut&Run), and RNA pol II (SRR4252922) signals centered on stranded and unstranded ...
This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...
A research team has identified NEAT1, a long non-coding RNA, as a key player in DNA repair. This discovery links RNA metabolism to genome stability and opens up potential new cancer treatments. Credit ...
Interest in RNA posttranscriptional modifications, particularly 5-methylcytosine (m5C), has surged in recent years. Studies have shown that m5C plays a key role in cellular processes and is closely ...
the NUT-BRD4 fusions in NUT carcinoma and the SS18 (SWI/SNF) fusions in synovial sarcoma(1, 2). (a) Table of the eight formalin-Fixed Paraffin-Embedded (FFPE) samples used for RNA-seq listing the ...
2015). In this review, we describe the mechanistic pathways how epithelial inflammation/injury promotes EMT and myofibroblast expansion and the evidence that BRD4 is an epigenetic regulator of EMT and ...
BRD4 knockdown changes the distribution of P-TEFb among nuclear soluble and chromatin and downregulates the elongation activity of RNA polymerase II. Inhibition of JNK kinase but not other MAP kinases ...
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