C&EN17d
Tether-Directed Electrosynthesis of Bicyclic [60]Fullerene Derivatives Fused with 5-Membered Azacycle and 13-Membered Carbocycle
Key Laboratory of Functional Molecular Solids, Ministry of Education, Anhui Laboratory of Molecule-Based Materials, and School of Chemistry and Materials Science, Anhui Normal University, Wuhu, Anhui ...
C&EN21d
Pfizer readies its next-generation COVID-19 antiviral
One spot they quickly identified for modification was the geminal dimethyl group on nirmatrelvir’s rigid fused bicyclic ring system. It’s prone to oxidation by CYP3A4 enzymes. “As part of ...
C&EN28d
Highly Diastereoselective Synthesis of 5/6-Fused Bicyclic Ring Systems via Radical Cyano Group Migration
Hefei National Research Center for Physical Sciences at the Microscale and Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, P. R. China ...