CRISPR: From Discovery To Clinic—And Charting A Path Forward
No doubt 2025 will usher in many more advances in CRISPR therapies, thanks to the FDA’s new Platform Technology Designation ...
pharmaphorum8d
CRISPR pioneers Doudna and Charpentier claim Nobel chemistry prize
Drs Emmanuelle Charpentier and Jennifer Doudna have won this year’s Nobel Prize for chemistry in recognition of their work on the gene-editing technology CRISPR/Cas9. Charpentier – currently ...
CRISPR system variant shows a novel DNA cleavage mechanism
Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, ...
The EMBO Journal5d
A CRISPR-Cas9 screen reveals genetic determinants of the cellular response to decitabine
A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...
‘Much-needed hope’ as CRISPR gene editing therapy recommended for sickle cell disease
The discovery of the CRISPR/Cas9 gene editing tool won two researchers, Emmanuelle Charpentier and Jennifer A. Doudna, the ...
Morocco World News4d
Gene Editing for Growth: How CRISPR Could Redefine Africa’s Agricultural Landscape
Africa is grappling with severe food insecurity in the wake of consecutive droughts, climate change, and ongoing conflicts, ...
AZoLifeSciences on MSN1d
CRISPR-Cas9 Off-Target Effects: Challenges and Solutions
The CRISPR-Cas9 system offers groundbreaking genome editing capabilities, yet off-target cleavage raises concerns about ...
Impacts5d
Unveiling the Power of CRISPR Screening in Modern Genomics
CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...
CRISPR technique helps reveal how bean genes could improve nitrogen fixation
Beans are a key food at the dietary level, boasting high nutritional value and constituting the most directly consumed legume ...