CRISPR system variant shows a novel DNA cleavage mechanism
Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, ...
AZoLifeSciences on MSN19h
CRISPR-Cas9 Off-Target Effects: Challenges and Solutions
The CRISPR-Cas9 system offers groundbreaking genome editing capabilities, yet off-target cleavage raises concerns about ...
Developmental biologists discover how a critical protein shapes gallbladder formation
The lab of Dr. Mark Magnuson, Louise B. McGavock Professor and professor of molecular physiology and biophysics at Vanderbilt ...
Activating complex regions of the genome to treat rare diseases: Researchers identify a a master epigenetic switch
Biomedical engineers at Duke University have demonstrated a promising new approach that could be used to treat a rare and ...
CRISPR: From Discovery To Clinic—And Charting A Path Forward
No doubt 2025 will usher in many more advances in CRISPR therapies, thanks to the FDA’s new Platform Technology Designation ...
New Vision on MSN2d
Magoola says cancer treatment invention awarded US patent
KAMPALA - Dr Matthias Magoola says the US Patent and Trademark Office (USPTO) has granted a patent for his invention of the first treatment of cancer using a novel composition of a guided Ribonucleic ...
The Observer2d
Ugandan secures US patent for cancer treatment
In a landmark achievement for both Uganda and the global medical community, the United States Patent and Trademark Office ...
Morocco World News4d
Gene Editing for Growth: How CRISPR Could Redefine Africa’s Agricultural Landscape
Africa is grappling with severe food insecurity in the wake of consecutive droughts, climate change, and ongoing conflicts, which are affecting millions across the continent.
The Scientist11d
What’s the Difference Between Cas9 and Cas12a Nucleases?
Both Cas9 and Cas12a cleave DNA, but they differ in how they cut the molecule.
Le Lézard14d
Mammoth Biosciences Announces New Results on NanoCas ? the First Efficient Ultracompact Extrahepatic Gene Editor
a novel Cas enzyme approximately one third the size of Cas9 ? which can be easily accommodated ... life-threatening and debilitating diseases. Founded by CRISPR pioneer and Nobel laureate Jennifer ...