We demonstrate that the introduction of constitutively active Notch3 into periventricular cells of embryonic day 9.5 mice causes the formation of choroid plexus tumors (CPTs). Tumors arose in the ...

Nature Research Intelligence Topics enable transformational understanding and discovery in research by categorising any document into meaningful, accessible topics. Read this blog to understand ...

AQP1, AQP3, AQP5, AQP7, AQP8, and AQP11 are expressed in the choroid plexus. AQP1, AQP3, AQP4 ... Corticosteroids are utilized for treating brain tumors. Surgical resection of the underlying lesion ...

Choroid plexus epithelium (CPE) also undergoes several senescent ... which occur in the natural aging process, are also induced by the tumor microenvironment. These include a loss of T cell CD28 ...

They confirmed this by identifying choroid plexus cells, the cell type that secretes cerebrospinal fluid into the ventricles of the brain, as the gateway for neuro-invasion. "The passage of ...

Brain Tumor Organoids Accurately Model Patient Response to CAR T Cell Therapy Dec. 9, 2024 — Researchers used lab-grown organoids created from tumors of individuals with glioblastoma (GBM ...

A pioneering new treatment promises to tackle a wider range of cancers, with fewer side-effects than conventional radiotherapy. It also takes less than a second. In a series of vast underground ...

Serum tumor markers were negative. Tests for paraneoplastic and voltage-gated potassium channel antibodies were negative, but antibodies to N-methyl-D-aspartate receptors (NMDARs) were identified ...

Most tonsil cancers are a type called squamous cell carcinoma. A small number of tonsil cancers are lymphomas. The information in this section is about squamous cell carcinoma. The treatment for ...

This is because they all grow quickly. Doctors put your neuroendocrine cancers into one of the 2 key groups: a neuroendocrine tumour (NET) or a neuroendocrine carcinoma (NEC). Neuroendocrine cancers ...

Background Choroid plexus (CP) enlargement has been suggested as a reliable marker of neuroinflammation in adult multiple sclerosis (MS). We investigated CP volume in patients with paediatric MS ...