"These findings illuminate a critical mechanism that connects local synaptic activity to the broader gene expression changes necessary for learning and memory," said Mark Dell'Acqua, professor of ...

The international team describes their results and the underlying molecular mechanism in Cell Metabolism. Ergothioneine is a natural compound found in certain fungi such as oyster or shiitake ...

But the exact mechanism is still unclear ... Citrate is synthesized in the mitochondrial matrix through the enzymatic action of citrate synthase (CS), which catalyzes the condensation of acetyl-CoA ...