In this study, the authors first used an AlphaScreen assay to identify a series of tryptophan-based cyclic peptide compounds with FXR-antagonistic activity, specifically those modified with a ...

Cyclic peptides, which combine characteristics ... DC646 selectively inhibited FXR signaling in the intestines of MASH model mice without affecting hepatic FXR signaling. Tissue distribution ...

Technology spending is now essential, with Indian IT firms poised for continued growth despite cyclic slowdowns. HDFC ...

The Big Crunch Followed by a Big Bang (Cyclic Model) The Cyclic Model adds a twist to the Big Crunch by proposing a sequence of big bangs following each crunch. It’s like hitting “reset” on ...

Govt approves Rs 11,440 crore equity infusion for RINL to keep it operational. The steel plant faces challenges with losses, ...

Robinson's New R88 Helicopter is designed for many missions, including executive transport, cargo transport, and even aerial ...

A novel strategy using lipid nanoparticles to reprogram liver immunity shows promise in generating antitumor responses ...

Southwest Research Institute (SwRI) collaborated with the U.S. Air Force to ensure fleet safety after a large crack was ...

Understanding the differences between enterprise and client SSDs — from NAND endurance to performance optimization — is ...