UCB, a global biopharmaceutical company, today announced positive data from studies involving its investigational pyrimidine nucleoside therapy, doxecitine (dC) and doxribtimine (dT), in people living ...

Pre-clinical data suggest the primary mechanism of action of doxecitine and doxribtimine is the incorporation of nucleosides deoxycytidine (dC) and deoxythymidine (dT) into skeletal muscle ...

Figure 2. Mechanisms of ferroptosis in MDS. Decitabine, a natural adenosine analogue of 2′-deoxycytidine nucleotide that is classified as an S-phase cell cycle-specific drug, exerts demethylation by ...

Tumors often arise in chronically inflamed, and thus immunologically highly active niches. While immune cells are able to recognize and remove transformed cells, tumors eventually escape the control ...

[Perhydroxyl Radical (HO2^(•)) as Inducer of the Isoprostane Lipid Peroxidation in Mitochondria].

Correspondence to Professor Julian Savulescu, Oxford Uehiro Centre for Practical Ethics, Oxford OX1 1PT, UK; julian.savulescu{at}philosophy.ox.ac.uk Charlie Gard was born at full term, apparently ...

Dipartimento di Chimica e Tecnologie del Farmaco, Università di Roma “La Sapienza”, P.le A. Moro 5, I-00185 Roma, ITALY ...