The surgical management of chronic wounds is a complex area of medicine that significantly influences patient outcomes and healthcare resources worldwide.

Tissue engineering is a set of methods that can replace or repair damaged or diseased tissues with natural, synthetic, or semisynthetic tissue mimics. These mimics can either be fully functional ...

Patients received evidence-based medical care, including intravenous antibiotic therapy and surgical debridement to remove necrotic and devitalized tissue. In one case, advanced negative pressure ...